B-Cure Laser Dental Pro’simg01
Mode of Action

LLLT involves the transmission of coherent red and near-infrared light energy at wavelengths that are able to pass into and through the body up to depths of 40 mm. Laser light may influence even deeper tissues due to its known cascade effect. As the laser passes into and through the body it generates a wide range of effects on physiological mechanisms and processes at the molecular and cellular and tissue levels.

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 References
1. Walsh, L.J., et al. 2006. “Low Level Laser Therapy (LLLT).” Chap. 13 in Oral Laser Application.Berlin: Quintessence.
2. Chung, H., et al. 2012. The nuts and bolts of low-level laser (light) therapy. Ann Biomed Eng, 40(2):516-33.

Main outcomes of photostimulation: Electrons transported in the chain for —

  • increased ATP production.
  • increased reactive oxygen species (ROS) production.
  • changes to the electric potential of cells and sub-cellular components.

Increased ATP production leads to enhanced activity of immune cells.

  • Triggers mast cell degranulation à release of pro-inflammatory cytokine TNF-alpha from the cells à increased infiltration of tissues by leukocytes.
  • Increases proliferation, maturation, and motility of fibroblasts.
  • Increases production of basic fibroblast growth factor.
  • Leads lymphocytes to become activated and proliferate more rapidly.
  • Makes epithelial cells become more motile, allowing wound sites to close more quickly.
  • Enhances ability of macrophages to act as phagocytes.
  • Increases synthesis of endorphins.

Increased reactive oxygen species (ROS) production activates transcription factors that cause protein synthesis that triggers further effects downstream.

  • Increased cell proliferation and migration
  • Modulation in levels of cytokines, growth factors, and inflammatory mediators.
  • Increased tissue oxygenation.
  • Increased collagen synthesis

Changes to the electric potential of cells and sub-cellular components include disruption of Na-K pump in membrane of nerve cells.

  • Leads to increased nerve activity.
  • Blocks pain nerve cells .
  • Relaxes smooth muscle.